The year is 1954. U.S. Marshal Teddy Daniels and his new -partner, Chuck Aule, have come to Shutter Island, home of Ashecliffe Hospital for the Criminally Insane, to investigate the disappearance of a patient. Multiple-murderess Rachel Solando is loose somewhere on this barren island, despite having been kept in a locked cell under constant surveillance. As a killer hurricane bears relentlessly down on them, a strange case takes on even darker, more sinister shades--with hints of radical experimentation, horrifying surgeries, and lethal countermoves made in the cause of a covert shadow war. No one is going to escape Shutter Island unscathed, because nothing at Ashecliffe Hospital is remotely what it seems.